Yazar "Bostancı, Mehmet Ömer" için listeleme
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Alpha-tocopherol decreases iron-induced hippocampal and nigral neuron loss
There are many studies about iron-induced neuronal hyperactivity and oxidative stress. Some reports also showed that iron levels rise in the brain in some neurodegenerative diseases such as Parkinson’s (PD) and Alzheimer’s ... -
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: The role of opioid receptors
Ülger, Fatma; Bozkurt, Ayhan; Bilge, S. Sırrı; İlkaya, Fatih; Dilek, Ahmet; Bostancı, Mehmet Ömer; Çiftçioğlu, Engin; Güldoğuş, Fırat (Lippincott Williams and Wilkins, 2009)BACKGROUND: In comparison with cutaneous pain, the role of ?2-adrenoceptor (?2-AR) agonists in visceral pain has not been extensively examined. We aimed to characterize the antinociceptive effect of IV dexmedetomidine on ... -
Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity: The role of L-type calcium channels in iron-induced neurotoxicity
Bostancı, Mehmet Ömer; Bağırıcı, Faruk (Informa Healthcare, 2013)Iron plays an important role in maintaining normal brain function. However, iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders such as ... -
Demirin neden olduğu purkinje hücre kaybı üzerine nitrik oksit sentaz inhibisyonunun koruyucu etkisi
Amaç: Demir, nöronal hiperaktivite ve oksidatif stresi indüklemek için sıklıkla kullanılan bir metaldir. Nitrik oksit sentaz (NOS) tarafından sentezlenen nitrik oksit ile hücre ölümü arasındaki ilişkiyi ortaya koyan bulgular ... -
Determining the factors that affect burnout and job satisfaction among academicians a sample application on the Hitit University
Yoleri, Sibel; Bostancı, Mehmet Ömer (Uluslararası Balkan Üniversitesi, 2012)Academicians are the most important components of the universities. Therefore, aim of this study is to identify the burnout and job satisfaction levels of academic personnel in Hitit University, and to evaluate the ... -
The effects of two different exercise programmes on adipose tissue hormones in sedentary middle-aged women
Özcan, Oğuzhan; Bostancı, Mehmet Ömer; Çiçek, Güner; Yamaner, Faruk (Informa Healthcare, 2015)Adipokines play an important role in obesity and related inflammatory disorders. We aimed to determine the effects of exercise training on serum adipokines. Forty sedentary women were randomly assigned to two groups as ... -
The effects of umbilical cord entanglement upon labor management and fetal health: retrospective case control study
Büyükkayacı Duman, Nuriye; Topuz, Şenay; Bostancı, Mehmet Ömer; Görkem, Ümit; Koçak, Derya Yüksel; Toğrul, Cihan; Güngör, Tayfun (Taylor and Francis Ltd, 2018)Objective: This retrospective study aimed at determining prognostic factors that paved the way for umbilical cord entanglement (UCE) and the effects of UCE upon labor management and fetal health. Methods: Sixty women who ... -
Hyperemesis gravidarum affects maternal sanity, thyroid hormones and fetal health: a prospective case control study
Büyükkayacı Duman, Nuriye; Özcan, Oğuzhan; Bostancı, Mehmet Ömer (Springer Verlag, 2015)Purpose: Hyperemesis gravidarum (HG) is a condition of severe nausea or vomiting accompanied by various complications during pregnancy. In the present study, we aimed to demonstrate the effects of HG on mother and fetus ... -
The impact of anemia and body mass index (BMI) on neuromotor development of preschool children
Özakar Akça, Selen; Bostancı, Mehmet Ömer (Associacao Medica Brasileira, 2017)Objective: According to data from the World Health Organization (WHO), anemia is a prevalent health problem that leads to increased morbidity and mortality, especially in preschool children. Anemia is recognized as a major ... -
Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy
Sefil, Fatih; Arık, Aliye E.; Acar, Meryem D.; Bostancı, Mehmet Ömer; Bağırıcı, Faruk; Kozan, Ramazan (E-Century Publishing Corporation, 2015)Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the ... -
Iron-induced cerebellar purkinje cell loss is ameliorated by flunarizine
Kozan, Ramazan; Bostancı, Mehmet Ömer; Nacar, Tuncer; Aslan, Ali; Bağırıcı, Faruk (Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (TÜBİTAK), 2009)Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkinje cells in rats and the possible neuroprotective effect of flunarizine, a ... -
Kisspeptin and hematologic parameters as predictive biomarkers for first-trimester abortions
Görkem, Ümit; Kan, Özgür; Bostancı, Mehmet Ömer; Taşkıran, Deniz; İnal, Hasan Ali (Logos Medical Publishing, 2021)Objective: Spontaneous abortion is the most common complication of early pregnancy, affecting up to 20% of recognized pregnancies. Kisspeptin is predominantly released by placental syncytiotrophoblasts, and regulates their ... -
Role of nitric oxide synthesis inhibitors in iron-induced nigral neurotoxicity: A mechanistic exploration
In the central nervous system, nitric oxide (NO) has been suggested to be a cell-to-cell signaling molecule that regulates guanylyl cyclase, aconitase, and iron regulatory protein. NO is also one of the substances that is ... -
Serum progranulin levels are elevated in infertile women with obesity
Görkem, Ümit; Öztürk İnal, Zeynep; İnal, Hasan Ali; Bostancı, Mehmet Ömer (Via Medica, 2018)Introduction: The aim of the present study was to investigate the changes in serum progranulin and sex hormone levels in infertile women with obesity. Material and methods: A total of 171 infertile women who had fertility ... -
Sıçan serebellumunda demir nörotoksisitesine karşı vitamin E'nin koruyucu etkisi
Kozan, Ramazan; Bostancı, Mehmet Ömer; Ayas, Bülent; Aslan, Ali; Bağırıcı, Faruk (Fırat Üniversitesi, 2009)Amaç: Bu çalışmada, intraserebroventriküler olarak verilen demirin, sıçan serebellar Purkinje hücrelerinde oluşturduğu nörotoksisiteye karşı yağda çözülebilen güçlü bir antioksidan olan vitamin E'nin (?-tokoferol) etkisini ...
