Yazar "Avşar, Orçun" için listeleme
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Analysis of missense SNPs in the SLC47A1 and SLC47A2 genes affecting the pharmacokinetics of metformin: Computational approach
Avşar, Orçun (SPRINGERNATURE, 2022)Background: Metformin as an anti-hyperglycaemic drug is commonly used for the treatment of type 2 diabetes mellitus (T2DM). The metformin response is variable due to the interindividual variation of pharmacokinetics which ... -
Association between Alzheimer’s disease, MAPT genemutation and some biochemical biomarkers
Şen, Ayşenur; Avşar, Orçun; Eliaçık, Sinan; Uysal Tan, Funda (TAYLOR & FRANCIS INC, 2024)Alzheimer’s Disease (AD) is a multifactorial neurodegenerativedisease and there is still no definitive treatment today. Earlydiagnosis of the disease is important, but there are almost nobiomarkers that can be used in early ... -
In Silico Analysis of miRNA-mediated ceRNAs as Potential Molecular Biomarkers in Glioblastoma
Avşar, Orçun (2021)Objectives: Glioblastoma multiforme (GBM) is defined as the most frequent and lethal form of the primary brain tumors in the central nervous system (CNS) in adults. Recent studies have focused on the identification of the ... -
Investigation of the relationship between ACAN geneVNTR polymorphism and Alzheimer’s disease inTurkish population
Keskin, Tuğba; Avşar, Orçun; Eliaçık, Sinan; Uysal Tan, Funda (TAYLOR & FRANCIS INC, 2024)Alzheimer’s disease is one of the most common causes of dementia and is a neurodegenerative disease that occurs with memory loss, loss of language, thinking and problem-solving skills. In this study, it was aimed to reveal ... -
Tümör Gelişiminde ve Tedavisinde Dopamin ve Dopamin Reseptörlerinin Rolü
Avşar, Orçun (2020)Önemli bir katekolamin nörotransmitter olan dopamin, santral sinir sisteminde ve sindirim sistemi, dalak ve pankreas gibi periferik dokularda sentez edilmektedir. Hem santral sinir sisteminde hem de pe-riferal sistemde ... -
Türk popülasyonunda ACAN geni VNTR polimorfizmi ile Alzheimer hastalığı arasındaki ilişkinin araştırılması
Keskin, Tuğba (Hitit Üniversitesi, 2022)Alzheimer hastalığı, en yaygın demans türü olup nöronların dejenere olmasına neden olan multifaktöriyel bir hastalıktır. Giderek dünya nüfusunun büyük bir bölümünü etkileyen Alzheimer hastalığı sinsi bir şekilde ilerlemektedir. ...
