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dc.contributor.authorEryilmaz, Fahri
dc.contributor.authorAhmed, Faheem
dc.contributor.authorRehmani, Asim K.
dc.contributor.authorKarimi, Sundas
dc.contributor.authorQazi, Aamna
dc.contributor.authorMustafa, Sufyan
dc.contributor.authorFarooque, Umar
dc.date.accessioned2021-11-01T15:06:02Z
dc.date.available2021-11-01T15:06:02Z
dc.date.issued2021
dc.identifier.issn2168-8184
dc.identifier.urihttps://doi.org/10.7759/cureus.15359
dc.identifier.urihttps://hdl.handle.net/11491/7474
dc.description.abstractIntroduction Degenerative scoliosis most commonly presents with lower back pain. Literature suggests that adults who have degenerative scoliosis are at greater risk of both hiatal hernia and gastroesophageal reflux disease (GERD). The objective of this study was to evaluate scoliosis as being the risk factor of GERD in adults. Materials and methods This prospective study was conducted at Dow University of Health Sciences over a period of two years (May 2018 to April 2020). The investigation included 210 participants with spinal disorders. The mean age was 71.6 +/- 9.6 years. The X-rays of the participants' whole spine were taken in a standing position, in the sagittal and corona' planes. Symptoms of GERD were measured through the quality of life and utility evaluation survey technology (QUEST) score, taking six points as cutoff values. The evaluation was done using radiographs to determine any relationship between spinal disorders and GERD. Negative values were analyzed in a right-sided convex curve while positive values in the left-sided convex curve were viewed in the coronal plane. Degenerative scoliosis was explained as a lumbar/thoracolumbar Cobb angle of more than 10 degrees. Univariate and multivariate logistic regression analyses were done to assess the risk factors related to GERD. Results Out. of 210 patients, 146 were found to have degenerative scoliosis at the level of the lumbar and thoracolumbar spine. Fifty-two patients had a right convex curve, and 94 had a left convex curve. Sixty-nine patients had GERD. According to the analysis of the multivariate logistic regression, the Cobb angle was highly related to GERD (p-value <0.05 and odds ratio of 1.031). The participants were grouped according to the Cobb angle of curve at the lumbar spine (less than 30 degrees with a large right-sided convex curve, 30 and more with a small curve, and more than 30+ degrees with a large left-sided convex curve). The study revealed that a large left-sided convex curve was highly related to GERD, with a p-value <0.05 and odds ratio of 10.935. Conclusions The left-sided large convex curve at the thoracolumbar or lumbar spine, especially when the Cobb angle was more than 30 degrees, was highly associated with GERD. Therefore, the symptoms of GERD should he monitored in the elderly population with degenerative scoliosis.en_US
dc.language.isoengen_US
dc.publisherCureus Incen_US
dc.relation.ispartofCureusen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectgastroesophageal reflux diseaseen_US
dc.subjectscoliosisen_US
dc.subjectquest scoreen_US
dc.subjectcobb angleen_US
dc.subjectsagittal planeen_US
dc.titleScoliosis and Gastroesophageal Reflux Disease in Adultsen_US
dc.typearticleen_US
dc.department[Belirlenecek]en_US
dc.identifier.volume13en_US
dc.identifier.issue5en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.department-temp[Eryilmaz, Fahri] Hitit Univ, Corum Erol Olcok Training & Res Hosp, Neurol Surg, Corum, Turkey; [Ahmed, Faheem] Civil Hosp, Trauma Ctr, Orthoped Surg, Karachi, Pakistan; [Rehmani, Asim K.] Natl Med Ctr, Neurol Surg, Karachi, Pakistan; [Karimi, Sundas] Dow Univ Hosp, Orthoped Surg, Karachi, Pakistan; [Qazi, Aamna; Nadeem, Zubia] Dow Univ Hlth Sci, Med, Karachi, Pakistan; [Mustafa, Sufyan] Civil Hosp, Dow Med Coll, Med, Karachi, Pakistan; [Zulfiqar, Arif] Dow Med Coll, Med & Surg, Karachi, Pakistan; [Sultan, Ayyaz A.] Calif Canc Associates Res & Excellence, Hematol Oncol, Fresno, CA USA; [Farooque, Umar] Dow Univ Hlth Sci, Neurol, Karachi, Pakistanen_US
dc.contributor.institutionauthor[Belirlenecek]
dc.identifier.doi10.7759/cureus.15359
dc.description.wospublicationidWOS:000657837600018en_US
dc.description.pubmedpublicationidPubMed: 34239791en_US


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