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dc.contributor.authorMert, Gurbet Ozge
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorMert, Kadir Ugur
dc.contributor.authorDogan, Volkan
dc.contributor.authorOzlek, Buelent
dc.contributor.authorCelik, Oguzhan
dc.contributor.authorKayikcioglu, Meral
dc.date.accessioned2021-11-01T15:02:59Z
dc.date.available2021-11-01T15:02:59Z
dc.date.issued2019
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.urihttps://doi.org/10.1111/ijcp.13358
dc.identifier.urihttps://hdl.handle.net/11491/6904
dc.description.abstractObjective There are lack of studies considering the suboptimal management of dyslipidemia especially in cardiology outpatient clinics. This study was conducted to assess the patient adherence to cholesterol treatment recommendations and attainment of low-density-lipoprotein cholesterol (LDL-C) goals. Methods EPHESUS (NCT02608645) is a national, observational and multicenter registry which has been designed as a cross-sectional study to allow inclusion of all consecutive patients with hypercholesterolemia in cardiology outpatient clinics. The present subgroup analyses of the EPHESUS trial included patients with known peripheral artery disease or atherosclerotic cerebrovascular disease, and coronary heart disease namely secondary prevention. Results The present analysis of the EPHESUS study included 1482 patients (62.79 +/- 10.4 years, 38.2% female) with secondary prevention from 40 sites in Turkey. Regarding recommended lipid targets for LDL-C, only 267 patients (18%) were below the target of 70 mg/dL. Females were significantly more off-target when compared with male patients (396, 85.5% vs 67, 14.5%; P = 0.017). Moreover, the achievement of LDL-C goal was significantly decreased with illiteracy (233, 19.2% vs 35, 13.1%; P = 0.02). Patients who think that the cholesterol treatment should be terminated when the cholesterol level of a patient has normalised were higher in the off-target group (34.0% vs 24.7%, P < 0.001). Besides, physician perceptions about LDL-C goal for secondary prevention were significantly related with LDL-C target attainment. Conclusions EPHESUS is an important study with large population in terms of representing real-life practice of the adherence to dyslipidemia guidelines in secondary prevention patients in Turkey. Perceptions, knowledge, and compliance with the guidelines for secondary prevention have increased, but it is far below from the desired levels even in cardiology outpatient clinics. There is a need for patients' and physicians' education regarding the treatment of hyperlipidemia.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Clinical Practiceen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keywords]en_US
dc.titleThe reasons of poor lipid target attainment for secondary prevention in real life practice: Results from EPHESUSen_US
dc.typearticleen_US
dc.department[Belirlenecek]en_US
dc.authoridCinier, Goksel / 0000-0001-5064-1816
dc.authoridMert, Kadir Ugur / 0000-0002-1331-5365
dc.authoridozdemir, ibrahim halil / 0000-0003-3953-4387
dc.authoridMERT, GURBET OZGE / 0000-0001-8350-9758
dc.identifier.volume73en_US
dc.identifier.issue9en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.department-temp[Mert, Gurbet Ozge] Eskisehir Yunus Emre State Hosp, Dept Cardiol, Eskisehir, Turkey; [Basaran, Ozcan; Dogan, Volkan; Ozlek, Buelent; Celik, Oguzhan; Ozlek, Eda; Cil, Cem; Biteker, Murat] Mugla Sitki Kocman Univ, Dept Cardiol, Fac Med, Mugla, Turkey; [Mert, Kadir Ugur] Eskisehir Osmangazi Univ, Dept Cardiol, Fac Med, Eskisehir, Turkey; [Ozdemir, Ibrahim Halil] Nizip State Hosp, Dept Cardiol, Gaziantep, Turkey; [Rencuzogullari, Ibrahim] Kafkas Univ, Dept Cardiol, Fac Med, Kars, Turkey; [Karadeniz, Fatma Ozpamuk] Erzurum Reg Training & Res Hosp, Dept Cardiol, Erzurum, Turkey; [Bekar, Lutfu; Kalcik, Macit] Hitit Univ, Dept Cardiol, Fac Med, Corum, Turkey; [Aktas, Muejdat] Kocaeli Univ, Fac Med Reg Training & Res Hosp, Dept Cardiol, Kocaeli, Turkey; [Resulzade, Mubariz Murat] Private Hosp Pk Hosp, Dept Cardiol, Kocaeli, Turkey; [Aksan, Gokhan] Sisli Hamidiye Etfal Res & Training Hosp, Dept Cardiol, Istanbul, Turkey; [Cinier, Goksel] Dr Siyami Ersek Thorac & Cardiovasc Surg Ctr, Dept Cardiol, Istanbul, Turkey; [Akay, Kadriye] Kocaeli State Hosp, Dept Cardiol, Kocaeli, Turkey; [Pekel, Nihat] Tekden Private Hosp, Dept Cardiol, Denizli, Turkey; [Senol, Utku] Eskisehir Acibadem Hosp, Dept Cardiol, Eskisehir, Turkey; [Kayikcioglu, Meral] Ege Univ, Dept Cardiol, Fac Med, Izmir, Turkeyen_US
dc.contributor.institutionauthor[Belirlenecek]
dc.identifier.doi10.1111/ijcp.13358
dc.authorwosidKAYIKCIOGLU, Meral / AAH-6687-2020
dc.authorwosidBekar, Lutfu / A-6945-2019
dc.authorwosidCinier, Goksel / Y-1715-2019
dc.authorwosidMert, Gurbet Ozge / AAH-7736-2019
dc.authorwosidMert, Kadir Ugur / D-6727-2016
dc.description.wospublicationidWOS:000483810100004en_US
dc.description.scopuspublicationid2-s2.0-85066839340en_US
dc.description.pubmedpublicationidPubMed: 31038781en_US


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