Güncel Gönderiler: Kimya Bölümü
Toplam kayıt 209, listelenen: 81-100
-
Magnetic nanocomposites of boron and Vitamin C
(Royal Society of Chemistry, 2017)Magnetic nanocomposites comprising elemental boron and vitamin C in the form of mono or bis(ascorbatoborate) complexes have been synthesized for targeted delivery/therapy applications. These nanocomposites were characterized ... -
Development and validation of a stability-indicating RP-LC method for the determination of anticancer drug epirubicin in pharmaceuticals
(Taylor and Francis Inc., 2014)In the present paper, sensitive, rapid, and different analytical methodology was developed for the determination of anticancer drug epirubicin (EPR). The mixture of epirubicin and moxifloxacin as internal standard was ... -
Determination of pKa values of some butyrophenones, their sensitive LC-UV analysis in pharmaceutical dosage forms and stress degradation behavior under ICH-recommended stress conditions
(2013)In this study, pKa values of some ionizable butyrophenones, namely, benperidol, droperidol, and haloperidol were determined using by the dependence of the retention factor on pH of the mobile phase. The effect of the mobile ... -
Optimization of the experimental conditions for macrolide antibiotics in high performance liquid chromatography by using response surface methodology and determination of tylosin in milk samples
(2011)The simple, rapid and sensitive liquid chromatographic separation of five macrolides (tilmicosin, erythromycin, tylosin, roxithromycin and josamycin) widely used in food producing animals was developed. Response surface ... -
Simultaneous determination and validation of some binary mixtures of antihypertensive drugs using ratio derivative spectrophotometric method
(Maik Nauka Publishing / Springer SBM, 2014)Ratio derivative spectrophotometric technique is presented for the rapid, accurate and precise simultaneous determination of olmesartan medoxomil (OLM), hydrochlorothiazide (HCT), and zofenopril (ZOF) as well as HCT binary ... -
A validated RP-LC method for salmeterol and fluticasone in their binary mixtures and their stress degradation behavior under ICH-recommended stress conditions
(Maik Nauka Publishing / Springer SBM, 2014)Simple, accurate, precise and fully validated analytical methods for the simultaneous determination of salmeterol xinafoate and fluticasone propionate in combined dosage forms have been developed. These drugs were exposed ... -
Determination of pKa values of some antipsychotic drugs by HPLC-correlations with the kamlet and taft solvatochromic parameters and HPLC analysis in dosage forms
(2013)In this study, ionization constant (pKa) values were determined by using the dependence of the retention factor on the pH of the mobile phase for four ionizable drugs, namely, risperidone (RI), clozapine (CL), olanzapine ... -
Fully validated simultaneous determination of bisoprolol fumarate and hydrochlorothiazide in their dosage forms using different voltammetric, chromatographic, and spectrophotometric analytical methods
(2013)Voltammetric, chromatographic, and spectrophotometric methods were developed for the simultaneous determination of bisoprolol fumarate (BIS) and hydrochlorothiazide (HCZ). Differential pulse and square wave voltammetry ... -
A validated stability-indicating RP-LC method for the simultaneous determination of amlodipine and perindopril in tablet dosage form and their stress degradation behavior under ICH-recommended stress conditions
(2013)A stability-indicating RP-LC assay method was developed for the simultaneous determination of the cardiovascular drugs amlodipine and perindopril in the presence of degradation products generated from forced decomposition ... -
Poly(HEMA-co-AA) microparticles for removal of aluminum: The reason for Alzheimer's
(Taylor and Francis Inc., 2017)Aluminum is one of the most toxic metals causing a variety of neurologic diseases, especially Alzheimer's disease. It is impossible to avoid contact with aluminum because of its existence in food to medications. Therefore, ... -
Electrostatic adsorption of asymmetric dimethyl arginine (adma) on poly (2-hydroxyethyl methacrylate-acrylic acid) nanoparticles
(Taylor and Francis Inc., 2017)Separation and purification of asymmetric dimethylarginine (ADMA) molecule, which is an important biomolecule in terms of cardiovascular diseases, is of great importance. Among the methods, the adsorption technique is of ... -
Synthesis and biological activity of new cycloalkylthiophene-Schiff bases and their Cr(III) and Zn(II) complexes
(Birkhauser Boston, 2010)A series of some novel Ethyl 2-((1-hydroxynaphthalen-2-yl)methyleneamino)- 5,6-dihydro-4H-cyclopenta[b]thiopehene-3-carboxylate, Ethyl 2-((1- hydroxynaphthalen- 2-yl)methyleneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3- ... -
Spectroscopic, antiproliferative and antiradical properties of Cu(II), Ni(II), and Zn(II) complexes with amino acid based Schiff bases
(Birkhauser Boston, 2014)Novel six Cu(II), Ni(II), and Zn(II) complexes with Schiff bases derived from 4-aminobenzoic acid with terephtaldehyde and amino acids (glycine, ?-alanine). Structures have been proposed from elemental analysis, UV-Vis, ... -
Synthesis of bis(thiosemicarbazone) derivatives: Definition, crystal structure, biological potential and computational analysis
(Taylor and Francis Ltd., 2018)(2-(2-(2-methoxyphenyl)hydrazono)cyclohexane-1,3-diylidene) bis(hydrazine carbothioamide) (L1), 4-(2-(-2,-6-bis(2-carbamothioylhydrazono) cyclohexylidene) hydrazinyl)benzoic acid (L2), and (2-(2-(4-bromophenyl) hydrazono) ... -
Modern Assay Techniques for Cancer Drugs: Electroanalytical and Liquid Chromatography Methods
(Taylor and Francis Ltd., 2018)In the past decades, patients who have chemotherapy treatment have considerably increased number. At this point, the development of rapid precise, and reliable methods are very important to analyze cancer drugs from their ... -
Electrochemical Approach on Mechanism of an Oral Progestin in Aqueous Media and its Fully Validated Detection via a Carbon-Metal Based Composite Sensor
(Wiley-VCH Verlag, 2018)Dienogest is a synthetic oral progestogen with unique pharmacological properties that is used orally in the treatment of endometrosis. The first time, the detailed electrochemical mechanism of dienogest is investigated in ... -
A Facile Strategy for Construction of Sensor for Detection of Ondansetron and Investigation of its Redox Behavior and Thermodynamic Parameters
(Wiley-VCH Verlag, 2019)A sodium dodecylsulfate-doped polypyrrole (SDS-PPy) film was elaborated on glassy carbon electrode (GCE) by an electrodeposition method in phosphate buffer solution (pH 2.0) containing pyrrole (Py) and sodium dodecyl sulfate ... -
Development and validation of a liquid chromatographic method for concurrent assay of weakly basic drug verapamil and amphoteric drug trandolapril in pharmaceutical formulations
(2012)The analysis of weakly basic drugs such as verapamil by reverse-phase liquid chromatography remains a problem, particularly when present in combination with other drugs such as amphoteric compounds like trandolapril. In ... -
Synthesis of {substituted-[(4-{[4-(carboxymethyl-carbamoyl)phenylimino] methyl}benzylidene)-amino]benzoylamino}carboxylic acids
(2008)Some novel derivatives of methotrexate like compounds 2a-f have been synthesized, using terephthalaldehyde, isophthalaldehyde, 4-aminobenzoic acid and amino acids (glycine, ?-alanine, L-glutamic acid). The structures of ... -
Synthesis of some novel derivatives of 2,6-diaminoanthraquinone dyes
(2008)In present study, some derivatives of 2,6-diaminoanthraquinone dyes are synthesized and their UV-visible spectra are investigated in various conditions. Ten compounds (1a-e) and (2a-e), two of which (1a, 1b) were previously ...
