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dc.contributor.authorBayraktar, Barış
dc.contributor.authorÖzemir, İbrahim Ali
dc.contributor.authorKefeli, Umut
dc.contributor.authorDemiral, Gökhan
dc.contributor.authorSağıroğlu, Jülide
dc.contributor.authorBayraktar, Onur
dc.contributor.authorAdalı Köroglu, Gupse
dc.contributor.authorÖzçelik, Alp
dc.contributor.authorTortum, Osman Baran
dc.date.accessioned2019-05-13T08:58:36Z
dc.date.available2019-05-13T08:58:36Z
dc.date.issued2015
dc.identifier.citationBayraktar, B., Özdemir, İ. A., Kefeli, U., Demiral, G., Sağıroğlu, J., Bayraktar, O., Adalı, G., Özçelik, A., Tortum, O. B. (2015). Colorectal stenting for palliation and as a bridge to surgery: a 5-year follow-up study. World Journal of Gastroenterology, 21(31), 9373-9379.en_US
dc.identifier.issn1007-9327
dc.identifier.urihttps://doi.org/10.3748/wjg.v21.i31.9373
dc.identifier.urihttps://hdl.handle.net/11491/1168
dc.description.abstractAIM: To evaluate the long-term effectiveness of colonic stents in colorectal tumors causing large bowel obstruction. METHODS: We retrospectively analyzed data from 49 patients with colorectal cancer who had undergone colorectal stent placement between January 2008 and January 2013. Patients' symptoms, characteristics and clinicopathological data were obtained by reviewing medical records. The obstruction was diagnosed clinically and radiologically. Histopathological diagnosis was achieved endoscopically. Technical success rate (TSR) was defined as the ratio of patients with correctly placed SEMS upon stent deployment across the entire stricture length to total number of patients. Clinical success rate (CSR) was defined as the ratio of patients with technical success and successful maintenance of stent function before elective surgery (regardless of number of SEMS deployed) to total number of patients. The surgical success rate (SSR) of colorectal stent as a bridge to surgery was defined as the ratio of patients with successful surgical procedures. Unsuccessful surgical outcomes were defined as being due to insufficient colonic decompression. The technical, clinical, surgical success rates and complications after stenting were assessed. RESULTS: The median age of patients was 64 (36 to 89). 44.9% of patients were male and 55.1% were female. Eighteen patients had the obstruction located in the rectum, 15 patients in the rectosigmoid region, 10 patients in the sigmoid region, and 6 patients had a tumor causing obstruction in the proximal colon. Each patient was categorized pathologically as stage 2 (32.7%, 16 patients) or stage 3 (42.9%, 21 patients) and 12 patients (24.4%) had metastatic disease. None of the patients received chemotherapy before stenting. Stenting was undertaken in 37 patients as a bridge to surgery, and in 12 patients stents were used for palliation. Median time to surgery after stenting was 30 ± 91.9 d. All surgery was completed in one single operation and thus no colostomy with stoma was needed. The median overall survival rate of patients with stage 2-3 colorectal cancer was 53.1 mo and stage 4 was 37.1 mo (P = 0.04). Metastatic colorectal patients who were treated palliatively with stents had backbone chemotherapy with oxaliplatin and/or irinotecan-based regimens plus antiangiogenic therapies, especially bevacizumab. Resolution of the obstruction and clinical improvement was achieved in all patients. The technical, clinical and surgical success rates were 95.9%, 100% and 94.6%, respectively. CONCLUSION: The efficacy and safety of colonic stents was demonstrated both as a bridge to surgery and for palliative decompression. In addition, results emphasize the importance of the skills of the endoscopist in colonic stenting. © The Author(s) 2015.en_US
dc.language.isoeng
dc.publisherBaishideng Publishing Group Inc.en_US
dc.relation.isversionof10.3748/wjg.v21.i31.9373en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 4.0 International (CC BY-NC 4.0)*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectColonic Decompressionen_US
dc.subjectColorectal Tumorsen_US
dc.subjectLarge Bowel Obstructionen_US
dc.subjectMetallic Stenten_US
dc.subjectPalliative Therapyen_US
dc.titleColorectal stenting for palliation and as a bridge to surgery: a 5-year follow-up studyen_US
dc.typearticleen_US
dc.relation.journalWorld Journal of Gastroenterologyen_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.identifier.volume21en_US
dc.identifier.issue31en_US
dc.identifier.startpage9373en_US
dc.identifier.endpage9379en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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