Yazar "Şanlı, Senem" için listeleme
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Analytical application of polymethylene blue-multiwalled carbon nanotubes modified glassy carbon electrode on anticancer drug irinotecan and determination of its ionization constant value
Karadaş Bakırhan, Nurgül; Şanlı, Senem; Akmeşe, Bediha; Doğan Topal, Burcu; Can, Alp; Özkan, Sibel Ayşıl (Elsevier B.V., 2013)The voltammetric behavior of anticancer drug irinotecan (IRT) was investigated at poly (methylene blue)/multi-walled carbon nanotube (PMB/MWCNT) modified glassy carbon electrode (GCE). The modified electrode surface was ... -
Bazı antifungal ilaçların ters faz sıvı kromatografik yöntemle analizleri için metot optimizasyonu
Başaran, Fatma (Hitit Üniversitesi Fen Bilimleri Enstitüsü, 2012)Bu çalışmada, mantar enfeksiyonu tedavisinde önemli bir yere sahip olan fentikonazol, itrakonazol, izokonazol, ketokonazol, mikonazol, ornidazol, tinidazol ve tiokonazolun iyonlaşma sabitleri su ve su-organik çözücü ... -
Determination of dissociation constants of folinic acid (leucovorin), 5-fluorouracil, and irinotecan in hydro-organic media by a spectrophotometry method
Şanlı, Nurullah; Şanlı, Senem; Alsancak, Güleren (2010)In this study, a multiwavelength spectrophotometry method was used for the determination of the dissociation constants of drugs used for treatment of colorectal cancer, folinic acid (leucovorin), 5-fluorouracil, and ... -
Determination of dissociation constants of some antifungal drugs by two different methods at 298 K
The dissociation constants of eight antifungal drugs (fenticonazole, isoconazole, itraconazole, ketoconazole, miconazole, ornidazole, tinidazole, tioconazole) have been determined in water and acetonitrile-water binary ... -
Determination of pK a values of cefdinir and cefixime by LC and spectrophotometric methods and their analysis in pharmaceutical dosage forms
Şanlı, Nurullah; Şanlı, Senem; Sızır, Ümit; Gümüştaş, Mehmet; Özkan, Sibel Ayşıl (Friedr. Vieweg und Sohn Verlags GmbH, 2011)The pK a values of cefdinir and cefixime, which are used in the treatment of bacterial infections, have been determined precisely in water and methanol-water binary mixtures (20% v/v) using spectrophotometric titration and ... -
Determination of pKa values of some antihypertensive drugs by liquid chromatography and simultaneous assay of lercanidipine and enalapril in their binary mixtures
Gümüştaş, Mehmet; Şanlı, Senem; Şanlı, Nurullah; Özkan, Sibel Ayşıl (Elsevier B.V., 2010)In this study, pKa values were determined using the dependence of the retention factor on the pH of the mobile phase for three ionizable substances, namely, enalapril, lercanidipine and ramipril (IS). The effect of the ... -
Determination of pKa values of some antipsychotic drugs by HPLC-correlations with the kamlet and taft solvatochromic parameters and HPLC analysis in dosage forms
Şanlı, Senem; Akmeşe, Bediha; Altun, Yüksel (2013)In this study, ionization constant (pKa) values were determined by using the dependence of the retention factor on the pH of the mobile phase for four ionizable drugs, namely, risperidone (RI), clozapine (CL), olanzapine ... -
Determination of pKa values of some butyrophenones, their sensitive LC-UV analysis in pharmaceutical dosage forms and stress degradation behavior under ICH-recommended stress conditions
Şanlı, Senem; Özkan, Sibel Ayşıl; Güney, Zeynep (2013)In this study, pKa values of some ionizable butyrophenones, namely, benperidol, droperidol, and haloperidol were determined using by the dependence of the retention factor on pH of the mobile phase. The effect of the mobile ... -
Determination of pKa values of some sulfonamides by LC and LC-PDA methods in acetonitrile-water binary mixtures
As constantes de dissociação de sete sulfonamidas antibióticas, sulfadiazina, sulfatiazol, sulfamerazina, sulfametazina, sulfamonometoxina, sulfadoxina e sulfametoxazol, foram determinadas em diferentes misturas binárias ... -
Determination of protonation constants of some tetracycline antibiotics by potentiometry and LC methods in water and acetonitrile-water binary mixtures
Şanlı, Senem; Şanlı, Nurullah; Alsancak, Güleren (2009)Uma estimativa acurada das constantes de dissociação de antibióticos tetraciclina em misturas binárias acetonitrila-água é muito importante para muitas técnicas de separação, como cromatografia líquida e eletroforese capilar ... -
Development and validation of a liquid chromatographic method for concurrent assay of weakly basic drug verapamil and amphoteric drug trandolapril in pharmaceutical formulations
The analysis of weakly basic drugs such as verapamil by reverse-phase liquid chromatography remains a problem, particularly when present in combination with other drugs such as amphoteric compounds like trandolapril. In ... -
Development and validation of a stability-indicating RP-LC method for the determination of anticancer drug epirubicin in pharmaceuticals
Kurbanoğlu, Sevinç; Bozal Palabıyık, Burçin; Gümüştaş, Mehmet; Şanlı, Senem; Uslu, Bengi; Özkan, Sibel Ayşıl (Taylor and Francis Inc., 2014)In the present paper, sensitive, rapid, and different analytical methodology was developed for the determination of anticancer drug epirubicin (EPR). The mixture of epirubicin and moxifloxacin as internal standard was ... -
The inhibition of steel corrosion in acidic solutions by a new Schiff base
Bakırhan, Nurgül K.; Asan, Abdurrahman; Çolak, Naki; Şanlı, Senem (Sociedad Chilena de Quimica, 2016)The inhibition effect of 2,2?- (((thiobis (4,1 phenylene)) bis(azanylylidene)) bis(methanylyidene)) bis(4-methoxyphenol) (BIS-IMIN) on the corrosion behavior of 304-stainless steel (SS) in 0.5 M HCl solution was studied ... -
Lösemi tedavisinde kullanılan bazı ilaçların iyonlaşma sabitlerinin su-organik çözücü ikili karışımlarında, spektroskopik ve ypsk yöntemler ile belirlenmesi ve bu ilaçların YPSK yöntemle eş zamanlı tayini
Canıtez, Pınar (Hitit Üniversitesi Fen Bilimleri Enstitüsü, 2012)Bu çalışmada, kanser hastalıkları arasında önemli bir yere sahip olan ve yurdumuzda da sıklıkla görülen lösemi hastalığının tedavisinde kullanılan doksorubisin, vinkristin, tioguanin ve daunorubisinin iyonlaşma sabitleri ... -
A novel RP-LC method for determination of pK a values of some anticancer agents and their assay
A simple, reliable, and rapid RP-LC method has been developed for the determination of some anticancer drugs (daunorubicin, doxorubicin and vincristine sulfate) in their dosage forms and human urine. These compounds are ... -
Optimization of separation of several sulfonamides in acetonitrile-water binary mixtures by using symmetry shield RP-8 column
Şanlı, Senem; Şanlı, Nurullah; Gökmeşe, Faruk; Gökmeşe, Ebru; Çubuk Demiralay, Ebru (Hacettepe University, 2009)In this work, the proportion of organic modifier of the hydro-organic mobile phase was optimized in order to separate twelve compounds namely sulfaguanidine, sulfanilamide, sulfadiazine, sulfathiazole, sulfamethazine, ... -
Optimization of the experimental conditions for macrolide antibiotics in high performance liquid chromatography by using response surface methodology and determination of tylosin in milk samples
Şanlı, Senem; Palabıyık, İsmail M.; Şanlı, Nurullah; Güzel Seydim, Zeynep B.; Alsancak, Güleren (2011)The simple, rapid and sensitive liquid chromatographic separation of five macrolides (tilmicosin, erythromycin, tylosin, roxithromycin and josamycin) widely used in food producing animals was developed. Response surface ... -
Simultaneous estimation of ceftazidime and ceftizoxime in pharmaceutical formulations by HPLC method
Şanlı, Senem; Şanlı, Nurullah; Gümüştaş, Mehmet; Özkan, Sibel Ayşıl; Karadaş, Nurullah; Aboul-Enein, Hassan Y. (2011)The aim of the present study was to develop a fast, sensitive and reliable method for rapid screening of cephalosporin injectable dosage forms namely ceftazidime and ceftizoxime to the detection of counterfeit and substandard ... -
Solvent effects on pKa values of some substituted sulfonamides in acetonitrile-water binary mixtures by the UV-spectroscopy method
The examination of the dissociation constants of sulfonamides is essential in drug-design studies and in explaining the biopharmaceutical properties of substances. The dissociation constants of ten common human and veterinary ... -
Spectrophotometric determination of acidity constants of some macrolides in acetonitrile-water binary mixtures
Şanlı, Senem; Şanlı, Nurullah; Alsancak, Güleren (2010)The acidity constants of eight macrolides (erythromycin, roxithromycin, oleandomycin, azithromycin, josamycin, tylosin tartrate, tilmicosin and spiramycin) have been determined in acetonitrile-water binary mixtures (30%, ...
